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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">patmedfar</journal-id><journal-title-group><journal-title xml:lang="ru">Пациентоориентированная медицина и фармация</journal-title><trans-title-group xml:lang="en"><trans-title>Patient-Oriented Medicine and Pharmacy</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-1924</issn><publisher><publisher-name>LLC Izdatelstvo OKI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37489/2949-1924-0037</article-id><article-id custom-type="edn" pub-id-type="custom">CKMQEL</article-id><article-id custom-type="elpub" pub-id-type="custom">patmedfar-64</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БЕЗОПАСНОСТЬ ЛЕКАРСТВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DRUG SAFETY</subject></subj-group></article-categories><title-group><article-title>Лекарственно-индуцированный уролитиаз у ребёнка, осложнённый острым обструктивным повреждением почек: клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Drug-induced urolithiasis in a child complicated by acute obstructive kidney injury: clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2062-0421</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шорманов</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shormanov</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шорманов Игорь Сергеевич — д. м. н., профессор, зав. кафедрой урологии с нефрологией</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Igor S. Shormanov — Doctor of Medicine, Professor, Head. Department of Urology with Nephrology</p><p>Yaroslavl</p></bio><email xlink:type="simple">i-s-shormanov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0686-0445</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щедров</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchedrov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щедров Дмитрий Николаевич — д. м. н., доцент кафедры урологии с нефрологией; зав. отделением детской уроандрологии</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Dmitriy N. Shchedrov — Doctor of Medical Sciences, Associate Professor of the Department of Urology with Nephrology; Head. Department of Pediatric Uroandrology</p><p>Yaroslavl</p></bio><email xlink:type="simple">shedrov.dmitry@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2464-572X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жигалов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhigalov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жигалов Сергей Алексеевич — к. м. н., доцент кафедры урологии с нефрологией</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Sergey A. Zhigalov — Ph. D., Associate Professor of the Department of Urology and Nephrology</p><p>Yaroslavl</p></bio><email xlink:type="simple">sergey.zhigalow@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4457-9694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарова</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Garova</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гарова Дарья Юрьевна — врач детский уролог-андролог </p><p>Ярославль</p></bio><bio xml:lang="en"><p>Daria Yu. Garova — doctor pediatric urologist-andrologist</p><p>Yaroslavl</p></bio><email xlink:type="simple">dar.garova@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3176-8229</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соколов Сергей Вячеславович — к. м. н., зам. главного врача по хирургической помощи</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Sergey V. Sokolov — Candidate of Medical Sciences, Deputy Chief Physician</p><p>Yaroslavl</p></bio><email xlink:type="simple">sokolovsergey@indox.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8651-279X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабунина</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Babunina</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабунина Екатерина Николаевна — студентка 5 курса педиатрического факультета</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Ekaterina N. Babunina — 5th year student of the Pediatric Faculty</p><p>Yaroslavl</p></bio><email xlink:type="simple">babuninakatusha2002@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ярославский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yaroslavl State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ярославский государственный медицинский университет» Министерства здравоохранения Российской Федерации; ГБУЗ Ярославской области «Областная детская клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yaroslavl State Medical University; Regional Children's Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБКУЗ Ярославской области «Центральная городская больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central City Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ Ярославской области «Областная детская клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Children's Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>27</day><month>03</month><year>2024</year></pub-date><volume>2</volume><issue>1</issue><fpage>15</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шорманов И.С., Щедров Д.Н., Жигалов С.А., Гарова Д.Ю., Соколов С.В., Бабунина Е.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Шорманов И.С., Щедров Д.Н., Жигалов С.А., Гарова Д.Ю., Соколов С.В., Бабунина Е.Н.</copyright-holder><copyright-holder xml:lang="en">Shormanov I.S., Shchedrov D.N., Zhigalov S.A., Garova D.Y., Sokolov S.V., Babunina E.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pomph.ru/jour/article/view/64">https://www.pomph.ru/jour/article/view/64</self-uri><abstract><p>Цефтриаксон-индуцированная мочекаменная болезнь — редкая форма мочекаменной болезни в детском возрасте, и ещё реже она сопровождается постренальным (обструктивным) острым повреждением почек. Развитие её на фоне острого хирургического заболевания брюшной полости, по поводу которого проводится антибактериальная терапия, представляется сложным как с точки зрения диагностики, так и лечения. Представлен случай развития мочекаменной болезни на фоне лечения аппендикулярного перитонита, осложнённой тяжёлым острым обструктивным повреждением почек, купированным малоинвазивными методами с последующим разрешением обструкции.</p></abstract><trans-abstract xml:lang="en"><p>Ceftriaxone-induced urolithiasis is a rare form of urolithiasis in childhood and is accompanied even less often by postrenal (obstructive) acute kidney injury. Its development against the background of acute surgical abdominal disease, for which antibacterial therapy is being performed, seems difficult both from the point of view of diagnosis and treatment. A case of the development of urolithiasis against the background of treatment of appendicular peritonitis complicated by severe acute obstructive kidney injury, which was stopped by minimally invasive methods with subsequent resolution of the obstruction, is presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мочекаменная болезнь</kwd><kwd>цефтриаксон</kwd><kwd>анурия</kwd><kwd>острое повреждение почек</kwd><kwd>перкутанная нефростомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>urolithiasis</kwd><kwd>ceftriaxone</kwd><kwd>anuria</kwd><kwd>acute kidney injury</kwd><kwd>percutaneous nephrostomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Du Y, Kang M, Mena J, Stoller ML, Ho SP, Li J. Structure and elemental composition of Ceftriaxone induced pediatric nephrolithiasis. 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