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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">patmedfar</journal-id><journal-title-group><journal-title xml:lang="ru">Пациентоориентированная медицина и фармация</journal-title><trans-title-group xml:lang="en"><trans-title>Patient-Oriented Medicine and Pharmacy</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-1924</issn><publisher><publisher-name>LLC Izdatelstvo OKI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37489/2949-1924-0125</article-id><article-id custom-type="edn" pub-id-type="custom">ZMNYSM</article-id><article-id custom-type="elpub" pub-id-type="custom">patmedfar-217</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОТОРИНОЛАРИНГОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OTORHINOLARYNGOLOGY</subject></subj-group></article-categories><title-group><article-title>О влиянии электронных сигарет на голос: наблюдательное исследование</article-title><trans-title-group xml:lang="en"><trans-title>About the effects of electronic cigarettes on the voice: observational study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8553-0489</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шиленкова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilenkova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шиленкова Виктория Викторовна — д. м. н., профессор, профессор кафедры оториноларингологии </p><p>Ярославль </p></bio><bio xml:lang="en"><p>Victoria V. Shilenkova — Dr. Sci. (Med.), Professor, Professor of the Department of Otolaryngology</p><p>Yaroslavl </p></bio><email xlink:type="simple">v.shilenkova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-8716-1695</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сыроваткина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Syrovatkina</surname><given-names>E. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сыроваткина Евгения Андреевна — врач-оториноларинголог</p><p>Нижний Новгород </p></bio><bio xml:lang="en"><p>Evgeniya A. Syrovatkina — otorhinolaryngologist </p><p>Nizhny Novgorod </p></bio><email xlink:type="simple">eugenia8607@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-9639-0872</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виноградова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinogradova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виноградова Ксения Александровна — студент-стажёр на кафедре оториноларингологии </p><p>Ярославль </p></bio><bio xml:lang="en"><p>Ksenia A. Vinogradova — Intern Student of the Department of Otolaryngology</p><p>Yaroslavl </p></bio><email xlink:type="simple">ksyu.krash@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ярославский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yaroslavl State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО Группа компаний «Персона»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Persona Group of Companies LLC</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2026</year></pub-date><volume>4</volume><issue>1</issue><fpage>5</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шиленкова В.В., Сыроваткина Е.А., Виноградова К.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Шиленкова В.В., Сыроваткина Е.А., Виноградова К.А.</copyright-holder><copyright-holder xml:lang="en">Shilenkova V.V., Syrovatkina E.А., Vinogradova K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pomph.ru/jour/article/view/217">https://www.pomph.ru/jour/article/view/217</self-uri><abstract><sec><title>Введение</title><p>Введение. Потребление электронных сигарет среди населения стремительно растёт, что обусловлено распространённым мнением о безопасности вейпов для здоровья и отсутствием развития зависимости по сравнению с обычными сигаретами.</p><p>Цель исследования — анализ патологии гортани у пользователей вейпов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В открытое, наблюдательное клиническое исследование вошли 194 человека в возрасте 19–66 лет (108 мужчин, 86 женщин) со стажем использования электронных сигарет от 1 до 6 лет и различными заболеваниями гортани: хронический катаральный ларингит (109), гиперпластический ларингит (46), отёк Рейнке (31), полип гортани (7), рак гортани (1). Алгоритм терапии определялся заболеванием гортани. Обязательным условием был отказ пациента от электронных сигарет. Пациенты с отёком Рейнке и опухолью гортани были прооперированы.</p></sec><sec><title>Результаты</title><p>Результаты. Оценить эффективность лечения удалось только у 69,6 % больных из-за низкой комплаентности и нежелания отказа от курения. Хороший исход болезни признан у 98 пациентов (72,6 %), но полностью отказались от курения только 29,6 % больных.</p></sec><sec><title>Выводы</title><p>Выводы. Установлена достоверная корреляция между фактом вейпинга и выраженностью гиперпластического процесса в гортани (r &gt;0,75, p &lt;0,05), но определить среднесуточное количество эпизодов использования пациентами электронных сигарет не удалось. Нет чёткой корреляционной взаимосвязи между стажем курения и тяжестью хронического заболевания гортани. Среди курящих с хроническими заболеваниями гортани высок процент некомплаентности в отношении динамического наблюдения, что связано с нежеланием отказа от курения и недопониманием негативного влияния вейпов на дыхательные пути.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. E-cigarettes use among the population is rapidly increasing, driven by the widespread belief that vaping is safe for health and does not cause of addiction compared to traditional cigarettes.</p></sec><sec><title>Objective</title><p>Objective. The aim of the study was to analyze laryngeal pathology in vape users.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. This open-label, observational clinical study included 194 participants aged 19–66 years (108 men, 86 women) with 1–6 years of e-cigarette use and various laryngeal diseases: chronic catarrhal laryngitis (109), hyperplastic laryngitis (46), Reinke's edema (31), laryngeal polyp (7), and laryngeal cancer (1). The treatment algorithm was determined by the laryngeal disease. Patients were required to stop using e-cigarettes. Patients with Reinke's edema and laryngeal tumor underwent surgery.</p></sec><sec><title>Results</title><p>Results. Treatment efficacy could only be assessed in 69.6 % of patients due to low compliance and reluctance to quit smoking. A good outcome was achieved in 98 patients (72.6 %), but only 29.6 % completely quit smoking.</p></sec><sec><title>Conclusions</title><p>Conclusions. A significant correlation was established between vaping and the severity of laryngeal hyperplasia (r &gt;0.75, p &lt;0.05), but it was not possible to determine the average daily number of e-cigarettes use episodes by patients. There is no clear correlation between smoking history and the severity of chronic laryngeal disease. Among smokers with chronic laryngeal disease, there is a high rate of noncompliance with follow-up care, which is due to reluctance to quit smoking and a lack of understanding of the negative impact of vaping on the respiratory tract.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>курение</kwd><kwd>электронные сигареты</kwd><kwd>вейпы</kwd><kwd>вейпинг</kwd><kwd>хронический ларингит</kwd><kwd>рак гортани</kwd><kwd>отёк Рейнке</kwd></kwd-group><kwd-group xml:lang="en"><kwd>smoking</kwd><kwd>electronic cigarettes</kwd><kwd>vaping</kwd><kwd>chronic laryngitis</kwd><kwd>laryngeal cancer</kwd><kwd>Reinke's edema</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Samarasekera U. WHO launches 10th report on the global tobacco epidemic. 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