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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">patmedfar</journal-id><journal-title-group><journal-title xml:lang="ru">Пациентоориентированная медицина и фармация</journal-title><trans-title-group xml:lang="en"><trans-title>Patient-Oriented Medicine and Pharmacy</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2949-1924</issn><publisher><publisher-name>LLC Izdatelstvo OKI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37489/2949-1924-0118</article-id><article-id custom-type="edn" pub-id-type="custom">YKOXEN</article-id><article-id custom-type="elpub" pub-id-type="custom">patmedfar-204</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНФЕКЦИОННЫЕ БОЛЕЗНИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INFECTIOUS DISEASES</subject></subj-group></article-categories><title-group><article-title>Жизнь после COVID-19: анализ долгосрочных симптомов по результатам опроса</article-title><trans-title-group xml:lang="en"><trans-title>Life after COVID-19: analysis of long-term symptoms based on survey results</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7315-3831</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салова</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Salova</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Салова Александра Леонидовна - к. м. н., ассистент кафедры педиатрии ИНПО</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Alexandra L. Salova - Cand. Sci. (Med.), Assistant of the Department of Pediatrics of the IPO, Department of Phthisiology</p><p>Yaroslavl</p></bio><email xlink:type="simple">domalexandra@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2153-8662</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мозжухина</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mozzhukhina</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мозжухина Лидия Ивановна — д. м. н., профессор, зав. кафедрой педиатрии ИНПО</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Lidiya I. Mozzhukhina - Dr. Sci. (Med.), Professor, Head of the Department of Pediatrics at the Institute of Pediatrics</p><p>Yaroslavl</p></bio><email xlink:type="simple">mli1612@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1722-8285</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кисельникова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselnikova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кисельникова Ольга Викторовна — к. м. н., доцент кафедры педиатрии ИНПО</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Olga V. Kiselnikova - Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics at the Institute of Pediatrics</p><p>Yaroslavl</p></bio><email xlink:type="simple">kiselnikova1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6214-6994</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Когут</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kogut</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Когут Татьяна Александровна - к. м. н., доцент кафедры педиатрии ИНПО</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Tatiana A. Kogut - Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics at the Institute of Pediatrics</p><p>Yaroslavl</p></bio><email xlink:type="simple">tkogut@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ярославский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yaroslavl State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2025</year></pub-date><volume>3</volume><issue>4</issue><fpage>55</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Салова А.Л., Мозжухина Л.И., Кисельникова О.В., Когут Т.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Салова А.Л., Мозжухина Л.И., Кисельникова О.В., Когут Т.А.</copyright-holder><copyright-holder xml:lang="en">Salova A.L., Mozzhukhina L.I., Kiselnikova O.V., Kogut T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pomph.ru/jour/article/view/204">https://www.pomph.ru/jour/article/view/204</self-uri><abstract><p>Актуальность. Постковидный синдром (ПКС) остаётся серьёзной медицинской и социальной проблемой, поскольку его симптомы могут сохраняться месяцами и даже годами после острой фазы COVID-19. По данным ВОЗ, до 6 % переболевших сталкиваются с ПКС, а по данным метаанализов — до 45 %. Это создаёт значительную нагрузку на систему здравоохранения и требует новых подходов к диагностике и реабилитации пациентов, особенно среди трудоспособного населения.Цель. Проанализировать особенности долгосрочных симптомов у пациентов, перенёсших COVID-19, на основе данных анкетирования, с целью выявления новых клинических феноменов, определения частоты и длительности их проявлений, а также изучения влияния демографических и клинических факторов на формирование ПКС.Материалы и методы. Исследование проведено среди 220 жителей г. Ярославля в 2024 г. (82,7 % женщин, средний возраст 33,8 года) с использованием электронной анкеты. Оценивались: наличие хронических заболеваний, статус вакцинации, течение и продолжительность симптомов. Применялись методы описательной статистики, корреляционный анализ, при уровне значимости p &lt;0,05.Результаты. У большинства участников сохранялись различные симптомы: усталость и когнитивные нарушения (83,8 %), бессонница (35 %), депрессивные состояния (52,4 %), выпадение волос (52,1 %). Часто отмечались сенсорные нарушения (85 % — потеря/искажение обоняния и вкуса), избирательное отвращение к продуктам, новые пищевые аллергические реакции (4 %), атипичные кожные проявления (6,8–11,4 %), необычные лекарственные реакции (13,6 %). Симптомы часто носили волнообразный характер (65 %) и сохранялись более трёх месяцев. Вакцинация снижала тя- жесть острой фазы, но не всегда предотвращала ПКС. Факторами риска были хронические заболевания, женский пол, аутоиммунные и метаболические нарушения.Выводы. Постковидный синдром — мультисистемное состояние, требующее индивидуального подхода к диагностике и реабилитации. Особое внимание рекомендуется уделять сенсорным, пищевым и кожным нарушениям, а также психоэмоциональной поддержке пациентов. Полученные данные могут служить основой для разработки новых клинических рекомендаций по ведению пациентов после COVID-19.</p></abstract><trans-abstract xml:lang="en"><p>Background. Post-covid syndrome (Long COVID) remains a serious medical and social problem, as its symptoms can persist for months or even years after the acute phase of COVID-19. According to the WHO, up to 6 % of those who have been ill experience Long COVID, and according to meta-analyses, up to 45 %. This creates a significant burden on the healthcare system and requires new approaches to the diagnosis and rehabilitation of patients, especially among the able-bodied population. Objective. To analyze the features of long-term symptoms in patients who have had COVID-19, based on survey data, in order to identify new clinical phenomena, determine the frequency and duration of their manifestations, as well as to study the influence of demographic and clinical factors on the formation of post-covid syndrome.Materials and methods. The study was conducted among 220 residents of Yaroslavl in 2024 (82.7 % women, average age 33.8 years) using an electronic questionnaire. The presence of chronic diseases, vaccination status, course and duration of symptoms were assessed. Methods of descriptive statistics, correlation analysis, and significance level p &lt;0.05 were used.Results. The majority of participants retained various symptoms: fatigue (83.8 %), cognitive impairment (85 %), insomnia (35 %), depressive states (52.4 %), hair loss (52.1 %). Sensory disturbances were often noted (85 % — loss/distortion of sense of smell and taste), selective aversion to foods, new food allergies (4 %), atypical skin manifestations (6.8–11.4 %), unusual drug reactions (13.6 %). The symptoms were often wave-like (65 %) and persisted for more than three months. Vaccination reduced the severity of the acute phase, but did not always prevent Long COVID. The risk factors were chronic diseases, female sex, autoimmune and metabolic disorders.Conclusions. Long COVID is a multisystem condition that requires an individual approach to diagnosis and rehabilitation. It is recommended to pay special attention to sensory, nutritional and skin disorders, as well as psychoemotional support for patients. The data obtained can serve as a basis for the development of new clinical guidelines for the management of patients after COVID-19.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>долгосрочные симптомы</kwd><kwd>вирус SARS-CoV-2</kwd><kwd>Long COVID</kwd><kwd>постковидный синдром</kwd><kwd>клинические феномены</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>long-term symptoms</kwd><kwd>SARS-CoV-2 virus</kwd><kwd>Long COVID</kwd><kwd>covid syndrome</kwd><kwd>clinical phenomena</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Асфандиярова Н.С. Постковидный синдром. Клиническая медицина. 2021;99(7-8):429-435.</mixed-citation><mixed-citation xml:lang="en">Asfandiyarova N.S. Post-COVID-19 syndrome. Clinical Medicine. 2021;99(7-8):429-435. 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Viruses. 2024 Dec 20;16(12):1955. doi: 10.3390/v16121955.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
