patmedfarПациентоориентированная медицина и фармацияPatient-Oriented Medicine and Pharmacy2949-1924LLC Izdatelstvo OKI10.37489/2949-1924-0086FJSNPPpatmedfar-161Research ArticleНЕВРОЛОГИЯNEUROLOGYГлимфатическая система у пациентов с рассеянным склерозомGlymphatic system in patients with multiple sclerosishttps://orcid.org/0000-0001-9078-589XСпиринН. Н.SpirinN. N.

Николай Николаевич Спирин, д. м. н., профессор, зав. кафедрой

кафедра нервных болезней с медицинской генетикой и нейрохирургией

Ярославль

РИНЦ AuthorID: 523232

Nikolay N. Spirin, Dr. Sci. (Med.), Professor, Head of the Department

Department of Nervous Diseases with Medical Genetics and Neurosurgery

Yaroslavl

РИНЦ AuthorID: 523232

nnspirin@yandex.ruhttps://orcid.org/0009-0004-4256-4178КрыцковаД. С.KrytskovaD. S.

Дарина Сергеевна Крыцкова, 

Ярославль

Darina S. Krytskova

Yaroslavl

ku.dara@mail.ruАксёноваА. С.AksenovaA. S.

Анастасия Сергеевна Аксёнова, 

Ярославль

Anastasia S. Aksenova

Yaroslavl

nastya.axs@yandex.ruФГБОУ ВО «Ярославский государственный медицинский университет»РоссияYaroslavl State Medical UniversityRussian Federation202503082025322227Copyright © Спирин Н.Н., Крыцкова Д.С., Аксёнова А.С., 20252025Спирин Н.Н., Крыцкова Д.С., Аксёнова А.С.Spirin N.N., Krytskova D.S., Aksenova A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pomph.ru/jour/article/view/161

   Глимфатическая система у пациентов с рассеянным склерозом (РС) представляет собой важный объект исследования, так как она играет ключевую роль в удалении метаболитов и поддержании гомеостаза в центральной нервной системе. При РС, характеризующемся демиелинизацией и воспалением, функции глимфатической системы могут быть нарушены, что приводит к накоплению токсичных веществ в мозге и усугублению нейродегенеративных процессов. Понимание взаимосвязи между глимфатической системой и РС откроет новые горизонты для потенциальных терапий, может помочь улучшить клиническое состояние пациентов и замедлить прогрессирование болезни.

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The authors declare that there are no conflicts of interest present.